KM 1146 structure

KM 1146

TL;DR: KM 1146 (CAS 876-76-6) is a chemical compound with molecular formula C12H15NO3S and molecular weight 253.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(3,4-dimethoxyphenyl)-5-methyl-1,3-thiazolidin-4-one

Also Known As: Mezolidon, 4-Thiazolidinone, 2-(3,4-dimethoxyphenyl)-5-methyl-, 2-(3,4-dimethoxyphenyl)-5-methyl-1,3-thiazolidin-4-one, 2-(3,4-Dimethoxyphenyl)-5-methylthiazolidin-4-one, 2-(3,4-Dimethoxyphenyl)-5-methyl-4-thiazolidinone

CAS: 876-76-6
Molecular Formula C12H15NO3S
Molecular Weight 253.08 g/mol
LogP 2.0
Topological Polar Surface Area 72.9 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 253.07727
Heavy Atoms 17
Complexity 287.0

Chemical Identifiers

CAS Number 876-76-6
SMILES CC1C(=O)NC(S1)C2=CC(=C(C=C2)OC)OC
InChIKey AUPNGGXXLZJAHC-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (8 patents) Pharmaceutical Intermediates (7 patents)

Product Overview

KM 1146 (CAS 876-76-6), with molecular formula C12H15NO3S and molecular weight 253.08 g/mol. IUPAC: 2-(3,4-dimethoxyphenyl)-5-methyl-1,3-thiazolidin-4-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of KM 1146

XLogP
2.0
TPSA (Topological Polar Surface Area)
72.9
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
17
Complexity
287.0
Exact Mass
253.07727
Monoisotopic Mass
253.07727
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of KM 1146

The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for KM 1146. The TPSA of 72.9 Ų falls within the moderate polarity range, balancing permeability and solubility for KM 1146. Following Lipinski's Rule of Five, KM 1146 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of KM 1146?

The CAS number of KM 1146 is 876-76-6.

What is the molecular formula of KM 1146?

The molecular formula of KM 1146 is C12H15NO3S.

What is the molecular weight of KM 1146?

The molecular weight of KM 1146 is 253.08 g/mol.

Where can I buy KM 1146?

You can request a quote for KM 1146 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for KM 1146?

Yes, KEHONG BIO provides custom synthesis services for KM 1146 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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