1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole
TL;DR: 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole (CAS 874615-36-8) is a chemical compound with molecular formula C18H17FN2O and molecular weight 296.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(4-fluorophenyl)methyl]-2-(oxolan-2-yl)benzimidazole
Also Known As: BAS 13175010, 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole, 2-{1-[(4-fluorophenyl)methyl]benzimidazol-2-yl}oxolane, 1-[(4-fluorophenyl)methyl]-2-(oxolan-2-yl)benzimidazole, 1-(4-Fluoro-benzyl)-2-(tetrahydro-furan-2-yl)-1H-benzoimidazole
| Molecular Formula | C18H17FN2O |
|---|---|
| Molecular Weight | 296.13 g/mol |
| LogP | 4.0752 |
| Topological Polar Surface Area | 27.05 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 296.13248 |
| Heavy Atoms | 22 |
| Complexity | 788.4573 |
Chemical Identifiers
| CAS Number | 874615-36-8 |
|---|---|
| SMILES | C1CC(OC1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F |
Product Overview
1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole (CAS 874615-36-8), with molecular formula C18H17FN2O and molecular weight 296.13 g/mol. IUPAC: 1-[(4-fluorophenyl)methyl]-2-(oxolan-2-yl)benzimidazole.
Chemical Property Profile of 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole
Property Insights of 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole
The XLogP value of 4.0752 indicates that 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 27.05 Ų, 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole?
The CAS number of 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole is 874615-36-8.
What is the molecular formula of 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole?
The molecular formula of 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole is C18H17FN2O.
What is the molecular weight of 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole?
The molecular weight of 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole is 296.13 g/mol.
Where can I buy 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole?
You can request a quote for 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-fluorobenzyl)-2-(tetrahydrofuran-2-yl)-1H-benzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.