5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate
TL;DR: 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate (CAS 87395-48-0) is a chemical compound with molecular formula C9H11F2N2O7P and molecular weight 328.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2R,3S,5R)-3-fluoro-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
Also Known As: Ffdump, 5'-Uridylic acid, 2',3'-dideoxy-3',5-difluoro-, 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate, 2',3'-dideoxy-3',5-difluorouridine 5'-(dihydrogen phosphate), [(2R,3S,5R)-3-fluoro-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
| Molecular Formula | C9H11F2N2O7P |
|---|---|
| Molecular Weight | 328.03 g/mol |
| LogP | -1.8 |
| Topological Polar Surface Area | 125.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 328.0272 |
| Heavy Atoms | 21 |
| Complexity | 536.0 |
Chemical Identifiers
| CAS Number | 87395-48-0 |
|---|---|
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)COP(=O)(O)O)F |
| InChIKey | DFYACPPPTKHKFG-UBKIQSJTSA-N |
Product Overview
5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate (CAS 87395-48-0), with molecular formula C9H11F2N2O7P and molecular weight 328.03 g/mol. IUPAC: [(2R,3S,5R)-3-fluoro-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate.
Chemical Property Profile of 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate
Property Insights of 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate
The XLogP value of -1.8 indicates that 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 125.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate. Following Lipinski's Rule of Five, 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate?
The CAS number of 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate is 87395-48-0.
What is the molecular formula of 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate?
The molecular formula of 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate is C9H11F2N2O7P.
What is the molecular weight of 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate?
The molecular weight of 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate is 328.03 g/mol.
Where can I buy 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate?
You can request a quote for 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate?
Yes, KEHONG BIO provides custom synthesis services for 5-Fluoro-(2',3')-dideoxy-3'-fluorouridine 5'-phosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.