trans-14-Hydroxytylophorine
TL;DR: trans-14-Hydroxytylophorine (CAS 87302-58-7) is a chemical compound with molecular formula C24H27NO5 and molecular weight 409.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(13aS,14S)-2,3,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizin-14-ol
Also Known As: trans-14-Hydroxytylophorine, (13aS,14S)-Tylophorinine, NCI60_040362, J2.718.304B, Dibenzo(f,H)pyrrolo(1,2-b)isoquinolin-14-ol, 9,11,12,13,13a,14-hexahydro-2,3,6,7-tetramethoxy-, (13as-trans)-
| Molecular Formula | C24H27NO5 |
|---|---|
| Molecular Weight | 409.19 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 60.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 409.18893 |
| Heavy Atoms | 30 |
| Complexity | 604.0 |
Chemical Identifiers
| CAS Number | 87302-58-7 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C3=C([C@@H]([C@@H]4CCCN4C3)O)C5=CC(=C(C=C25)OC)OC)OC |
| InChIKey | JWHWLMNMGLICQZ-MHECFPHRSA-N |
Product Overview
trans-14-Hydroxytylophorine (CAS 87302-58-7), with molecular formula C24H27NO5 and molecular weight 409.19 g/mol. IUPAC: (13aS,14S)-2,3,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizin-14-ol.
Chemical Property Profile of trans-14-Hydroxytylophorine
Property Insights of trans-14-Hydroxytylophorine
The XLogP value of 3.6 indicates that trans-14-Hydroxytylophorine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.4 Ų falls within the moderate polarity range, balancing permeability and solubility for trans-14-Hydroxytylophorine. Following Lipinski's Rule of Five, trans-14-Hydroxytylophorine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of trans-14-Hydroxytylophorine?
The CAS number of trans-14-Hydroxytylophorine is 87302-58-7.
What is the molecular formula of trans-14-Hydroxytylophorine?
The molecular formula of trans-14-Hydroxytylophorine is C24H27NO5.
What is the molecular weight of trans-14-Hydroxytylophorine?
The molecular weight of trans-14-Hydroxytylophorine is 409.19 g/mol.
Where can I buy trans-14-Hydroxytylophorine?
You can request a quote for trans-14-Hydroxytylophorine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for trans-14-Hydroxytylophorine?
Yes, KEHONG BIO provides custom synthesis services for trans-14-Hydroxytylophorine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.