amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- structure

amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-

TL;DR: amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- (CAS 87263-93-2) is a chemical compound with molecular formula C55H90N4O17 and molecular weight 1078.63 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1R,3S,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-[[N'-[3-(dimethylamino)propyl]-N-ethylcarbamimidoyl]amino]-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid

Also Known As: DAPEG, Guanido-amphotericin B, N-(N'-(3-Dimethylaminopropyl)-N''-ethylguanyl)amphotericin B, Amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-, (1R,3S,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-[[N'-[3-(Dimethylamino)propyl]-N-ethylcarbamimidoyl]amino]-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid

CAS: 87263-93-2
Molecular Formula C55H90N4O17
Molecular Weight 1078.63 g/mol
LogP 1.2598
Topological Polar Surface Area 333.25 Ų
Hydrogen Bond Donors 13
Hydrogen Bond Acceptors 18
Rotatable Bonds 9
Exact Mass 1078.6301
Heavy Atoms 76
Complexity 1963.1708

Chemical Identifiers

CAS Number 87263-93-2
SMILES CCNC(=NCCCN(C)C)N[C@H]1[C@@H]([C@H](O[C@H]([C@H]1O)O[C@@H]\2C[C@H]3[C@@H]([C@H](C[C@](O3)(C[C@H](CC(C(CCC(C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]([C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C2)C)O)C)C)O)O)O)O)O)O)O)C(=O)O)C)O

Product Overview

amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- (CAS 87263-93-2), with molecular formula C55H90N4O17 and molecular weight 1078.63 g/mol. IUPAC: (1R,3S,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-[[N'-[3-(dimethylamino)propyl]-N-ethylcarbamimidoyl]amino]-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-

XLogP
1.2598
TPSA (Topological Polar Surface Area)
333.25
Hydrogen Bond Donors
13
Hydrogen Bond Acceptors
18
Rotatable Bonds
9
Heavy Atoms
76
Complexity
1963.1708
Exact Mass
1078.6301
Monoisotopic Mass
1078.6301
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-

The XLogP value of 1.2598 suggests moderate lipophilicity, balancing water solubility and membrane permeability for amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-. The TPSA of 333.25 Ų indicates high polarity, suggesting amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- has 13 hydrogen bond donor(s) and 18 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-?

The CAS number of amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- is 87263-93-2.

What is the molecular formula of amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-?

The molecular formula of amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- is C55H90N4O17.

What is the molecular weight of amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-?

The molecular weight of amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- is 1078.63 g/mol.

Where can I buy amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-?

You can request a quote for amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)-?

Yes, KEHONG BIO provides custom synthesis services for amphotericin B, N-(N'-(3-dimethylaminopropyl)-N''-ethylguanyl)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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