3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine
TL;DR: 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine (CAS 87190-84-9) is a chemical compound with molecular formula C10H10F3N5O4 and molecular weight 321.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione
Also Known As: 3'-N3-5-CF3-ddU, 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine, 3'-Azido-2',3'-dideoxy-5-(trifluoromethyl)uridine, 3 -Azido-2 ,3 -dideoxy-5-trifluoromethyluridine, 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
| Molecular Formula | C10H10F3N5O4 |
|---|---|
| Molecular Weight | 321.07 g/mol |
| LogP | 0.6 |
| Topological Polar Surface Area | 93.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 3 |
| Exact Mass | 321.06848 |
| Heavy Atoms | 22 |
| Complexity | 571.0 |
Chemical Identifiers
| CAS Number | 87190-84-9 |
|---|---|
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)N=[N+]=[N-] |
| InChIKey | LYWDBOUHROZMIU-RRKCRQDMSA-N |
Product Overview
3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine (CAS 87190-84-9), with molecular formula C10H10F3N5O4 and molecular weight 321.07 g/mol. IUPAC: 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-(trifluoromethyl)pyrimidine-2,4-dione.
Chemical Property Profile of 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine
Property Insights of 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine. The TPSA of 93.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine. Following Lipinski's Rule of Five, 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine?
The CAS number of 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine is 87190-84-9.
What is the molecular formula of 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine?
The molecular formula of 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine is C10H10F3N5O4.
What is the molecular weight of 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine?
The molecular weight of 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine is 321.07 g/mol.
Where can I buy 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine?
You can request a quote for 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine?
Yes, KEHONG BIO provides custom synthesis services for 3'-Azido-2',3'-dideoxy-5-trifluoromethyluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.