Tpl2 Kinase Inhibitor
TL;DR: Tpl2 Kinase Inhibitor (CAS 871307-18-5) is a chemical compound with molecular formula C21H14ClFN6 and molecular weight 404.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile
Also Known As: Tpl2 Kinase Inhibitor, Tpl2 Kinase Inhibitor 1, Tpl2 Kinase, Tpl2-IN-2p, 4-((3-Chloro-4-fluorophenyl)amino)-6-((pyridin-3-ylmethyl)amino)-1,7-naphthyridine-3-carbonitrile
| Molecular Formula | C21H14ClFN6 |
|---|---|
| Molecular Weight | 404.10 g/mol |
| LogP | 5.04468 |
| Topological Polar Surface Area | 86.52 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 404.09525 |
| Heavy Atoms | 29 |
| Complexity | 1223.2471 |
Chemical Identifiers
| CAS Number | 871307-18-5 |
|---|---|
| SMILES | C1=CC(=CN=C1)CNC2=NC=C3C(=C2)C(=C(C=N3)C#N)NC4=CC(=C(C=C4)F)Cl |
Product Overview
Tpl2 Kinase Inhibitor (CAS 871307-18-5), with molecular formula C21H14ClFN6 and molecular weight 404.10 g/mol. IUPAC: 4-(3-chloro-4-fluoroanilino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile.
Chemical Property Profile of Tpl2 Kinase Inhibitor
Property Insights of Tpl2 Kinase Inhibitor
The XLogP value of 5.04468 indicates that Tpl2 Kinase Inhibitor is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.52 Ų falls within the moderate polarity range, balancing permeability and solubility for Tpl2 Kinase Inhibitor. Following Lipinski's Rule of Five, Tpl2 Kinase Inhibitor has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tpl2 Kinase Inhibitor?
The CAS number of Tpl2 Kinase Inhibitor is 871307-18-5.
What is the molecular formula of Tpl2 Kinase Inhibitor?
The molecular formula of Tpl2 Kinase Inhibitor is C21H14ClFN6.
What is the molecular weight of Tpl2 Kinase Inhibitor?
The molecular weight of Tpl2 Kinase Inhibitor is 404.10 g/mol.
Where can I buy Tpl2 Kinase Inhibitor?
You can request a quote for Tpl2 Kinase Inhibitor directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tpl2 Kinase Inhibitor?
Yes, KEHONG BIO provides custom synthesis services for Tpl2 Kinase Inhibitor and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.