F1816-0329 structure

F1816-0329

TL;DR: F1816-0329 (CAS 868377-39-3) is a chemical compound with molecular formula C21H18ClN3O3S2 and molecular weight 459.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(4-chloro-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)-4-pyrrolidin-1-ylsulfonylbenzamide

Also Known As: F1816-0329, N-[(2Z)-4-chloro-3-(prop-2-yn-1-yl)-2,3-dihydro-1,3-benzothiazol-2-ylidene]-4-(pyrrolidine-1-sulfonyl)benzamide, N-(4-chloro-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)-4-pyrrolidin-1-ylsulfonylbenzamide, (Z)-N-(4-chloro-3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)-4-(pyrrolidin-1-ylsulfonyl)benzamide, N-(4-chloro-3-prop-2-ynyl-benzothiazol-2-ylidene)-4-pyrrolidin-1-ylsulfonyl-benzamide

CAS: 868377-39-3
Molecular Formula C21H18ClN3O3S2
Molecular Weight 459.05 g/mol
LogP 3.515
Topological Polar Surface Area 71.74 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 459.04782
Heavy Atoms 30
Complexity 1326.5591

Chemical Identifiers

CAS Number 868377-39-3
SMILES C#CCN1C2=C(C=CC=C2Cl)SC1=NC(=O)C3=CC=C(C=C3)S(=O)(=O)N4CCCC4

Product Overview

F1816-0329 (CAS 868377-39-3), with molecular formula C21H18ClN3O3S2 and molecular weight 459.05 g/mol. IUPAC: N-(4-chloro-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)-4-pyrrolidin-1-ylsulfonylbenzamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F1816-0329

XLogP
3.515
TPSA (Topological Polar Surface Area)
71.74
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
30
Complexity
1326.5591
Exact Mass
459.04782
Monoisotopic Mass
459.04782
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F1816-0329

The XLogP value of 3.515 indicates that F1816-0329 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.74 Ų falls within the moderate polarity range, balancing permeability and solubility for F1816-0329. Following Lipinski's Rule of Five, F1816-0329 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F1816-0329?

The CAS number of F1816-0329 is 868377-39-3.

What is the molecular formula of F1816-0329?

The molecular formula of F1816-0329 is C21H18ClN3O3S2.

What is the molecular weight of F1816-0329?

The molecular weight of F1816-0329 is 459.05 g/mol.

Where can I buy F1816-0329?

You can request a quote for F1816-0329 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F1816-0329?

Yes, KEHONG BIO provides custom synthesis services for F1816-0329 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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