F1805-0325 structure

F1805-0325

TL;DR: F1805-0325 (CAS 868221-05-0) is a chemical compound with molecular formula C18H16N4OS2 and molecular weight 368.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-[3,4-dihydro-1H-isoquinolin-2-yl(thiophen-2-yl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol

Also Known As: F1805-0325, 5-((3,4-dihydroisoquinolin-2(1H)-yl)(thiophen-2-yl)methyl)thiazolo[3,2-b][1,2,4]triazol-6-ol, 5-[(1,2,3,4-tetrahydroisoquinolin-2-yl)(thiophen-2-yl)methyl]-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol, 5-[3,4-dihydro-1H-isoquinolin-2-yl(thiophen-2-yl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol

CAS: 868221-05-0
Molecular Formula C18H16N4OS2
Molecular Weight 368.08 g/mol
LogP 3.7056
Topological Polar Surface Area 53.66 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 3
Exact Mass 368.07657
Heavy Atoms 25
Complexity 1020.99896

Chemical Identifiers

CAS Number 868221-05-0
SMILES C1CN(CC2=CC=CC=C21)C(C3=CC=CS3)C4=C(N5C(=NC=N5)S4)O

Product Overview

F1805-0325 (CAS 868221-05-0), with molecular formula C18H16N4OS2 and molecular weight 368.08 g/mol. IUPAC: 5-[3,4-dihydro-1H-isoquinolin-2-yl(thiophen-2-yl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F1805-0325

XLogP
3.7056
TPSA (Topological Polar Surface Area)
53.66
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
3
Heavy Atoms
25
Complexity
1020.99896
Exact Mass
368.07657
Monoisotopic Mass
368.07657
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F1805-0325

The XLogP value of 3.7056 indicates that F1805-0325 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.66 Ų, F1805-0325 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1805-0325 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F1805-0325?

The CAS number of F1805-0325 is 868221-05-0.

What is the molecular formula of F1805-0325?

The molecular formula of F1805-0325 is C18H16N4OS2.

What is the molecular weight of F1805-0325?

The molecular weight of F1805-0325 is 368.08 g/mol.

Where can I buy F1805-0325?

You can request a quote for F1805-0325 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F1805-0325?

Yes, KEHONG BIO provides custom synthesis services for F1805-0325 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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