F1805-0158
TL;DR: F1805-0158 (CAS 868220-16-0) is a chemical compound with molecular formula C23H23FN4OS and molecular weight 422.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[(4-benzylpiperidin-1-yl)-(4-fluorophenyl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol
Also Known As: F1805-0158, 5-[(4-benzylpiperidin-1-yl)(4-fluorophenyl)methyl]-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol, 5-((4-benzylpiperidin-1-yl)(4-fluorophenyl)methyl)thiazolo[3,2-b][1,2,4]triazol-6-ol, 5-[(4-benzylpiperidin-1-yl)-(4-fluorophenyl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol
| Molecular Formula | C23H23FN4OS |
|---|---|
| Molecular Weight | 422.16 g/mol |
| LogP | 4.6796 |
| Topological Polar Surface Area | 53.66 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 422.15765 |
| Heavy Atoms | 30 |
| Complexity | 1117.2891 |
Chemical Identifiers
| CAS Number | 868220-16-0 |
|---|---|
| SMILES | C1CN(CCC1CC2=CC=CC=C2)C(C3=CC=C(C=C3)F)C4=C(N5C(=NC=N5)S4)O |
Product Overview
F1805-0158 (CAS 868220-16-0), with molecular formula C23H23FN4OS and molecular weight 422.16 g/mol. IUPAC: 5-[(4-benzylpiperidin-1-yl)-(4-fluorophenyl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol.
Chemical Property Profile of F1805-0158
Property Insights of F1805-0158
The XLogP value of 4.6796 indicates that F1805-0158 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.66 Ų, F1805-0158 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1805-0158 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1805-0158?
The CAS number of F1805-0158 is 868220-16-0.
What is the molecular formula of F1805-0158?
The molecular formula of F1805-0158 is C23H23FN4OS.
What is the molecular weight of F1805-0158?
The molecular weight of F1805-0158 is 422.16 g/mol.
Where can I buy F1805-0158?
You can request a quote for F1805-0158 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1805-0158?
Yes, KEHONG BIO provides custom synthesis services for F1805-0158 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.