F1805-0140
TL;DR: F1805-0140 (CAS 868220-05-7) is a chemical compound with molecular formula C21H19ClFN5OS and molecular weight 443.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[[4-(3-chlorophenyl)piperazin-1-yl]-(3-fluorophenyl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol
Also Known As: F1805-0140, 5-{[4-(3-chlorophenyl)piperazin-1-yl](3-fluorophenyl)methyl}-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol, 5-((4-(3-chlorophenyl)piperazin-1-yl)(3-fluorophenyl)methyl)thiazolo[3,2-b][1,2,4]triazol-6-ol, 5-[[4-(3-chlorophenyl)piperazin-1-yl]-(3-fluorophenyl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol
| Molecular Formula | C21H19ClFN5OS |
|---|---|
| Molecular Weight | 443.10 g/mol |
| LogP | 4.2005 |
| Topological Polar Surface Area | 56.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 443.0983 |
| Heavy Atoms | 30 |
| Complexity | 1187.0848 |
Chemical Identifiers
| CAS Number | 868220-05-7 |
|---|---|
| SMILES | C1CN(CCN1C2=CC(=CC=C2)Cl)C(C3=CC(=CC=C3)F)C4=C(N5C(=NC=N5)S4)O |
Product Overview
F1805-0140 (CAS 868220-05-7), with molecular formula C21H19ClFN5OS and molecular weight 443.10 g/mol. IUPAC: 5-[[4-(3-chlorophenyl)piperazin-1-yl]-(3-fluorophenyl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol.
Chemical Property Profile of F1805-0140
Property Insights of F1805-0140
The XLogP value of 4.2005 indicates that F1805-0140 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.9 Ų, F1805-0140 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1805-0140 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1805-0140?
The CAS number of F1805-0140 is 868220-05-7.
What is the molecular formula of F1805-0140?
The molecular formula of F1805-0140 is C21H19ClFN5OS.
What is the molecular weight of F1805-0140?
The molecular weight of F1805-0140 is 443.10 g/mol.
Where can I buy F1805-0140?
You can request a quote for F1805-0140 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1805-0140?
Yes, KEHONG BIO provides custom synthesis services for F1805-0140 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.