F1805-0135
TL;DR: F1805-0135 (CAS 868220-00-2) is a chemical compound with molecular formula C21H20FN5OS and molecular weight 409.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[(3-fluorophenyl)-(4-phenylpiperazin-1-yl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol
Also Known As: F1805-0135, 5-((3-fluorophenyl)(4-phenylpiperazin-1-yl)methyl)thiazolo[3,2-b][1,2,4]triazol-6-ol, 5-[(3-fluorophenyl)(4-phenylpiperazin-1-yl)methyl]-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol, 5-[(3-fluorophenyl)-(4-phenylpiperazin-1-yl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol
| Molecular Formula | C21H20FN5OS |
|---|---|
| Molecular Weight | 409.14 g/mol |
| LogP | 3.5471 |
| Topological Polar Surface Area | 56.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 409.13727 |
| Heavy Atoms | 29 |
| Complexity | 1120.5264 |
Chemical Identifiers
| CAS Number | 868220-00-2 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)C(C3=CC(=CC=C3)F)C4=C(N5C(=NC=N5)S4)O |
Product Overview
F1805-0135 (CAS 868220-00-2), with molecular formula C21H20FN5OS and molecular weight 409.14 g/mol. IUPAC: 5-[(3-fluorophenyl)-(4-phenylpiperazin-1-yl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol.
Chemical Property Profile of F1805-0135
Property Insights of F1805-0135
The XLogP value of 3.5471 indicates that F1805-0135 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.9 Ų, F1805-0135 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1805-0135 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1805-0135?
The CAS number of F1805-0135 is 868220-00-2.
What is the molecular formula of F1805-0135?
The molecular formula of F1805-0135 is C21H20FN5OS.
What is the molecular weight of F1805-0135?
The molecular weight of F1805-0135 is 409.14 g/mol.
Where can I buy F1805-0135?
You can request a quote for F1805-0135 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1805-0135?
Yes, KEHONG BIO provides custom synthesis services for F1805-0135 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.