F1805-0051
TL;DR: F1805-0051 (CAS 868219-52-7) is a chemical compound with molecular formula C22H22FN5OS and molecular weight 423.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[[4-(2-fluorophenyl)piperazin-1-yl]-(4-methylphenyl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol
Also Known As: F1805-0051, 5-{[4-(2-fluorophenyl)piperazin-1-yl](4-methylphenyl)methyl}-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol, 5-((4-(2-fluorophenyl)piperazin-1-yl)(p-tolyl)methyl)thiazolo[3,2-b][1,2,4]triazol-6-ol, 5-[[4-(2-fluorophenyl)piperazin-1-yl]-(4-methylphenyl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol
| Molecular Formula | C22H22FN5OS |
|---|---|
| Molecular Weight | 423.15 g/mol |
| LogP | 3.85552 |
| Topological Polar Surface Area | 56.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 423.15292 |
| Heavy Atoms | 30 |
| Complexity | 1163.9661 |
Chemical Identifiers
| CAS Number | 868219-52-7 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C(C2=C(N3C(=NC=N3)S2)O)N4CCN(CC4)C5=CC=CC=C5F |
Product Overview
F1805-0051 (CAS 868219-52-7), with molecular formula C22H22FN5OS and molecular weight 423.15 g/mol. IUPAC: 5-[[4-(2-fluorophenyl)piperazin-1-yl]-(4-methylphenyl)methyl]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-ol.
Chemical Property Profile of F1805-0051
Property Insights of F1805-0051
The XLogP value of 3.85552 indicates that F1805-0051 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.9 Ų, F1805-0051 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1805-0051 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1805-0051?
The CAS number of F1805-0051 is 868219-52-7.
What is the molecular formula of F1805-0051?
The molecular formula of F1805-0051 is C22H22FN5OS.
What is the molecular weight of F1805-0051?
The molecular weight of F1805-0051 is 423.15 g/mol.
Where can I buy F1805-0051?
You can request a quote for F1805-0051 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1805-0051?
Yes, KEHONG BIO provides custom synthesis services for F1805-0051 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.