F1726-0181
TL;DR: F1726-0181 (CAS 868152-89-0) is a chemical compound with molecular formula C21H17FN2O3S and molecular weight 396.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(5Z)-2,4-dioxo-5-[(E)-3-phenylprop-2-enylidene]-1,3-thiazolidin-3-yl]-N-(4-fluorophenyl)propanamide
Also Known As: F1726-0181, 3-[(5Z)-2,4-DIOXO-5-[(2E)-3-PHENYLPROP-2-EN-1-YLIDENE]-1,3-THIAZOLIDIN-3-YL]-N-(4-FLUOROPHENYL)PROPANAMIDE, 3-((Z)-2,4-dioxo-5-((E)-3-phenylallylidene)thiazolidin-3-yl)-N-(4-fluorophenyl)propanamide, 3-[(5Z)-2,4-dioxo-5-[(E)-3-phenylprop-2-enylidene]-1,3-thiazolidin-3-yl]-N-(4-fluorophenyl)propanamide, 3-[5-((2E)-3-phenylprop-2-enylidene)-2,4-dioxo(1,3-thiazolidin-3-yl)]-N-(4-flu orophenyl)propanamide
| Molecular Formula | C21H17FN2O3S |
|---|---|
| Molecular Weight | 396.09 g/mol |
| LogP | 4.447 |
| Topological Polar Surface Area | 66.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 396.0944 |
| Heavy Atoms | 28 |
| Complexity | 939.8829 |
Chemical Identifiers
| CAS Number | 868152-89-0 |
|---|---|
| SMILES | C1=CC=C(C=C1)/C=C/C=C\2/C(=O)N(C(=O)S2)CCC(=O)NC3=CC=C(C=C3)F |
Product Overview
F1726-0181 (CAS 868152-89-0), with molecular formula C21H17FN2O3S and molecular weight 396.09 g/mol. IUPAC: 3-[(5Z)-2,4-dioxo-5-[(E)-3-phenylprop-2-enylidene]-1,3-thiazolidin-3-yl]-N-(4-fluorophenyl)propanamide.
Chemical Property Profile of F1726-0181
Property Insights of F1726-0181
The XLogP value of 4.447 indicates that F1726-0181 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.48 Ų falls within the moderate polarity range, balancing permeability and solubility for F1726-0181. Following Lipinski's Rule of Five, F1726-0181 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1726-0181?
The CAS number of F1726-0181 is 868152-89-0.
What is the molecular formula of F1726-0181?
The molecular formula of F1726-0181 is C21H17FN2O3S.
What is the molecular weight of F1726-0181?
The molecular weight of F1726-0181 is 396.09 g/mol.
Where can I buy F1726-0181?
You can request a quote for F1726-0181 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1726-0181?
Yes, KEHONG BIO provides custom synthesis services for F1726-0181 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.