![1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione structure](/static/products/868/868144-33-6.png)
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione
概要：1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione（CAS 868144-33-6）是一种化学化合物，分子式为C25H26FN3O4，分子量为451.19 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
1'-[3-(dimethylamino)propyl]-4'-[(3-fluoro-4-methylphenyl)-hydroxymethylidene]-1-methylspiro[indole-3,5'-pyrrolidine]-2,2',3'-trione
又称：1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione, 1'-[3-(dimethylamino)propyl]-4'-[(3-fluoro-4-methylphenyl)-hydroxymethylidene]-1-methylspiro[indole-3,5'-pyrrolidine]-2,2',3'-trione
| 分子式 | C25H26FN3O4 |
|---|---|
| 分子量 | 451.19 g/mol |
| LogP | 2.63812 |
| 拓扑极性表面积 | 81.16 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 5 |
| 可旋转键数 | 5 |
| 精确质量 | 451.19073 |
| 重原子数 | 33 |
| 复杂度 | 1205.8882 |
化学标识符
| CAS 编号 | 868144-33-6 |
|---|---|
| SMILES | CC1=C(C=C(C=C1)C(=C2C(=O)C(=O)N(C23C4=CC=CC=C4N(C3=O)C)CCCN(C)C)O)F |
产品概述
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione（CAS 868144-33-6），分子式为C25H26FN3O4，分子量为451.19 g/mol。IUPAC名：1'-[3-(dimethylamino)propyl]-4'-[(3-fluoro-4-methylphenyl)-hydroxymethylidene]-1-methylspiro[indole-3,5'-pyrrolidine]-2,2',3'-trione。
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione化学性质概览
属性洞察：1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的XLogP值为2.63812，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为81.16 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione有1个氢键供体和5个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的CAS号是多少？
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的CAS号为868144-33-6。
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的分子式是什么？
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的分子式为C25H26FN3O4。
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的分子量是多少？
1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的分子量为451.19 g/mol。
在哪里可以购买1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione？
您可以直接向科弘生物询价1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的定制合成服务？
是的，科弘生物提供1'-[3-(dimethylamino)propyl]-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1-methyl-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。