![1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione structure](/static/products/868/868144-27-8.png)
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione
概要：1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione（CAS 868144-27-8）是一种化学化合物，分子式为C26H28FN3O4，分子量为465.21 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
1'-[3-(dimethylamino)propyl]-1-ethyl-4'-[(3-fluoro-4-methylphenyl)-hydroxymethylidene]spiro[indole-3,5'-pyrrolidine]-2,2',3'-trione
又称：1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione, 1'-[3-(dimethylamino)propyl]-1-ethyl-4'-[(3-fluoro-4-methylphenyl)-hydroxymethylidene]spiro[indole-3,5'-pyrrolidine]-2,2',3'-trione
| 分子式 | C26H28FN3O4 |
|---|---|
| 分子量 | 465.21 g/mol |
| LogP | 3.02822 |
| 拓扑极性表面积 | 81.16 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 5 |
| 可旋转键数 | 6 |
| 精确质量 | 465.2064 |
| 重原子数 | 34 |
| 复杂度 | 1222.2765 |
化学标识符
| CAS 编号 | 868144-27-8 |
|---|---|
| SMILES | CCN1C2=CC=CC=C2C3(C1=O)C(=C(C4=CC(=C(C=C4)C)F)O)C(=O)C(=O)N3CCCN(C)C |
产品概述
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione（CAS 868144-27-8），分子式为C26H28FN3O4，分子量为465.21 g/mol。IUPAC名：1'-[3-(dimethylamino)propyl]-1-ethyl-4'-[(3-fluoro-4-methylphenyl)-hydroxymethylidene]spiro[indole-3,5'-pyrrolidine]-2,2',3'-trione。
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione化学性质概览
属性洞察：1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的XLogP值为3.02822，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为81.16 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione有1个氢键供体和5个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的CAS号是多少？
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的CAS号为868144-27-8。
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的分子式是什么？
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的分子式为C26H28FN3O4。
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的分子量是多少？
1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的分子量为465.21 g/mol。
在哪里可以购买1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione？
您可以直接向科弘生物询价1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione的定制合成服务？
是的，科弘生物提供1'-[3-(dimethylamino)propyl]-1-ethyl-3'-(3-fluoro-4-methylbenzoyl)-4'-hydroxy-1,1',2,5'-tetrahydrospiro[indole-3,2'-pyrrole]-2,5'-dione及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。