HR 375
TL;DR: HR 375 (CAS 867-56-1) is a chemical compound with molecular formula C23H25ClFN3O and molecular weight 413.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
HR 375
1-(4-fluorophenyl)-4-(4-isoquinolin-3-ylpiperazin-1-yl)butan-1-one;hydrochloride
Also Known As: HR 375, 1-(4-fluorophenyl)-4-(4-isoquinolin-3-ylpiperazin-1-yl)butan-1-one hydrochloride, 3-(4-(3-(4-Fluorobenzoyl)propyl)-1-piperazinyl)isoquinoline hcl, 3-(4-(3-(4-fluorobenzoyl)propyl)-1-piperazinyl)isoquinolinehcl, 1-(4-fluorophenyl)-4-(4-isoquinolin-3-ylpiperazin-1-yl)butan-1-one,hydrochloride
| Molecular Formula | C23H25ClFN3O |
|---|---|
| Molecular Weight | 413.17 g/mol |
| LogP | 4.5808 |
| Topological Polar Surface Area | 36.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 413.16702 |
| Heavy Atoms | 29 |
| Complexity | 500.0 |
Chemical Identifiers
| CAS Number | 867-56-1 |
|---|---|
| SMILES | C1CN(CCN1CCCC(=O)C2=CC=C(C=C2)F)C3=CC4=CC=CC=C4C=N3.Cl |
| InChIKey | JZTJTZLBUIZNCX-UHFFFAOYSA-N |
Product Overview
HR 375 (CAS 867-56-1), with molecular formula C23H25ClFN3O and molecular weight 413.17 g/mol. IUPAC: 1-(4-fluorophenyl)-4-(4-isoquinolin-3-ylpiperazin-1-yl)butan-1-one;hydrochloride.
Chemical Property Profile of HR 375
Property Insights of HR 375
The XLogP value of 4.5808 indicates that HR 375 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.4 Ų, HR 375 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, HR 375 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of HR 375?
The CAS number of HR 375 is 867-56-1.
What is the molecular formula of HR 375?
The molecular formula of HR 375 is C23H25ClFN3O.
What is the molecular weight of HR 375?
The molecular weight of HR 375 is 413.17 g/mol.
Where can I buy HR 375?
You can request a quote for HR 375 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for HR 375?
Yes, KEHONG BIO provides custom synthesis services for HR 375 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.