7-Ethyl-10-Hydroxycamptothecin
TL;DR: 7-Ethyl-10-Hydroxycamptothecin (CAS 86639-52-3) is a chemical compound with molecular formula C22H20N2O5 and molecular weight 392.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
Also Known As: 7-Ethyl-10-hydroxycamptothecin, SN 38 lactone, SN 38, Camptothecin analog, Deruxtecan analog
| Molecular Formula | C22H20N2O5 |
|---|---|
| Molecular Weight | 392.14 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 100.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 392.1372 |
| Heavy Atoms | 29 |
| Complexity | 820.0 |
Chemical Identifiers
| CAS Number | 86639-52-3 |
|---|---|
| SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)O |
| InChIKey | FJHBVJOVLFPMQE-QFIPXVFZSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
7-Ethyl-10-Hydroxycamptothecin (CAS 86639-52-3), with molecular formula C22H20N2O5 and molecular weight 392.14 g/mol. IUPAC: (19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 7-Ethyl-10-Hydroxycamptothecin
Property Insights of 7-Ethyl-10-Hydroxycamptothecin
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 7-Ethyl-10-Hydroxycamptothecin. The TPSA of 100.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-Ethyl-10-Hydroxycamptothecin. Following Lipinski's Rule of Five, 7-Ethyl-10-Hydroxycamptothecin has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Ethyl-10-Hydroxycamptothecin?
The CAS number of 7-Ethyl-10-Hydroxycamptothecin is 86639-52-3.
What is the molecular formula of 7-Ethyl-10-Hydroxycamptothecin?
The molecular formula of 7-Ethyl-10-Hydroxycamptothecin is C22H20N2O5.
What is the molecular weight of 7-Ethyl-10-Hydroxycamptothecin?
The molecular weight of 7-Ethyl-10-Hydroxycamptothecin is 392.14 g/mol.
Where can I buy 7-Ethyl-10-Hydroxycamptothecin?
You can request a quote for 7-Ethyl-10-Hydroxycamptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Ethyl-10-Hydroxycamptothecin?
Yes, KEHONG BIO provides custom synthesis services for 7-Ethyl-10-Hydroxycamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.