N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide
TL;DR: N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide (CAS 866154-05-4) is a chemical compound with molecular formula C11H4ClF2N3OS and molecular weight 298.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide
Also Known As: N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide, N-(4-Chloro-5-cyanothiazol-2-yl)-3,4-difluorobenzamide, N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzenecarboxamide
| Molecular Formula | C11H4ClF2N3OS |
|---|---|
| Molecular Weight | 298.97 g/mol |
| LogP | 3.19868 |
| Topological Polar Surface Area | 65.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 298.97318 |
| Heavy Atoms | 19 |
| Complexity | 695.73413 |
Chemical Identifiers
| CAS Number | 866154-05-4 |
|---|---|
| SMILES | C1=CC(=C(C=C1C(=O)NC2=NC(=C(S2)C#N)Cl)F)F |
Product Overview
N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide (CAS 866154-05-4), with molecular formula C11H4ClF2N3OS and molecular weight 298.97 g/mol. IUPAC: N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide.
Chemical Property Profile of N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide
Property Insights of N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide
The XLogP value of 3.19868 indicates that N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.78 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide. Following Lipinski's Rule of Five, N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide?
The CAS number of N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide is 866154-05-4.
What is the molecular formula of N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide?
The molecular formula of N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide is C11H4ClF2N3OS.
What is the molecular weight of N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide?
The molecular weight of N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide is 298.97 g/mol.
Where can I buy N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide?
You can request a quote for N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-chloro-5-cyano-1,3-thiazol-2-yl)-3,4-difluorobenzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.