1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone
TL;DR: 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone (CAS 866145-22-4) is a chemical compound with molecular formula C12H10F3NO and molecular weight 241.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(1-ethylindol-3-yl)-2,2,2-trifluoroethanone
Also Known As: 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone, 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoroethan-1-one, 1-(1-ethylindol-3-yl)-2,2,2-trifluoroethanone, 1-Ethyl-3-(trifluoroacetyl)-1H-indole, J2.224.701H
| Molecular Formula | C12H10F3NO |
|---|---|
| Molecular Weight | 241.07 g/mol |
| LogP | 3.4062 |
| Topological Polar Surface Area | 22.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 241.07144 |
| Heavy Atoms | 17 |
| Complexity | 568.6247 |
Chemical Identifiers
| CAS Number | 866145-22-4 |
|---|---|
| SMILES | CCN1C=C(C2=CC=CC=C21)C(=O)C(F)(F)F |
Product Overview
1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone (CAS 866145-22-4), with molecular formula C12H10F3NO and molecular weight 241.07 g/mol. IUPAC: 1-(1-ethylindol-3-yl)-2,2,2-trifluoroethanone.
Chemical Property Profile of 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone
Property Insights of 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone
The XLogP value of 3.4062 indicates that 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 22.0 Ų, 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone?
The CAS number of 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone is 866145-22-4.
What is the molecular formula of 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone?
The molecular formula of 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone is C12H10F3NO.
What is the molecular weight of 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone?
The molecular weight of 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone is 241.07 g/mol.
Where can I buy 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone?
You can request a quote for 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone?
Yes, KEHONG BIO provides custom synthesis services for 1-(1-ethyl-1H-indol-3-yl)-2,2,2-trifluoro-1-ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.