![2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide structure](/static/products/866/866138-47-8.png)
2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide
TL;DR: 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide (CAS 866138-47-8) is a chemical compound with molecular formula C18H14ClN3O2S and molecular weight 371.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-chlorophenyl)-N-[(4-methoxyphenyl)methylideneamino]-1,3-thiazole-4-carboxamide
Also Known As: 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide, 2-(4-chlorophenyl)-N-[(4-methoxyphenyl)methylideneamino]-1,3-thiazole-4-carboxamide
| Molecular Formula | C18H14ClN3O2S |
|---|---|
| Molecular Weight | 371.05 g/mol |
| LogP | 4.236 |
| Topological Polar Surface Area | 63.58 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 371.04953 |
| Heavy Atoms | 25 |
| Complexity | 889.44446 |
Chemical Identifiers
| CAS Number | 866138-47-8 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C=NNC(=O)C2=CSC(=N2)C3=CC=C(C=C3)Cl |
Product Overview
2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide (CAS 866138-47-8), with molecular formula C18H14ClN3O2S and molecular weight 371.05 g/mol. IUPAC: 2-(4-chlorophenyl)-N-[(4-methoxyphenyl)methylideneamino]-1,3-thiazole-4-carboxamide.
Chemical Property Profile of 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide
Property Insights of 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide
The XLogP value of 4.236 indicates that 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.58 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide. Following Lipinski's Rule of Five, 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide?
The CAS number of 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide is 866138-47-8.
What is the molecular formula of 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide?
The molecular formula of 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide is C18H14ClN3O2S.
What is the molecular weight of 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide?
The molecular weight of 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide is 371.05 g/mol.
Where can I buy 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide?
You can request a quote for 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-chlorophenyl)-N'-[(E)-(4-methoxyphenyl)methylidene]-1,3-thiazole-4-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.