8T-0312
TL;DR: 8T-0312 (CAS 866137-49-7) is a chemical compound with molecular formula C19H17ClF3N5O3 and molecular weight 455.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(3-oxo-4H-1,4-benzoxazin-6-yl)piperazine-1-carboxamide
Also Known As: 8T-0312, 4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(3-oxo-4H-1,4-benzoxazin-6-yl)piperazine-1-carboxamide, 4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)piperazine-1-carboxamide, 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)tetrahydro-1(2H)-pyrazinecarboxamide, 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(3,4-dihydro-3-oxo-2H-1,4-benzoxazin-6-yl)-1-piperazinecarboxamide
| Molecular Formula | C19H17ClF3N5O3 |
|---|---|
| Molecular Weight | 455.10 g/mol |
| LogP | 3.4388 |
| Topological Polar Surface Area | 86.8 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 455.0972 |
| Heavy Atoms | 31 |
| Complexity | 1025.3334 |
Chemical Identifiers
| CAS Number | 866137-49-7 |
|---|---|
| SMILES | C1CN(CCN1C2=C(C=C(C=N2)C(F)(F)F)Cl)C(=O)NC3=CC4=C(C=C3)OCC(=O)N4 |
Product Overview
8T-0312 (CAS 866137-49-7), with molecular formula C19H17ClF3N5O3 and molecular weight 455.10 g/mol. IUPAC: 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(3-oxo-4H-1,4-benzoxazin-6-yl)piperazine-1-carboxamide.
Chemical Property Profile of 8T-0312
Property Insights of 8T-0312
The XLogP value of 3.4388 indicates that 8T-0312 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 8T-0312. Following Lipinski's Rule of Five, 8T-0312 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8T-0312?
The CAS number of 8T-0312 is 866137-49-7.
What is the molecular formula of 8T-0312?
The molecular formula of 8T-0312 is C19H17ClF3N5O3.
What is the molecular weight of 8T-0312?
The molecular weight of 8T-0312 is 455.10 g/mol.
Where can I buy 8T-0312?
You can request a quote for 8T-0312 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8T-0312?
Yes, KEHONG BIO provides custom synthesis services for 8T-0312 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.