8T-0267
TL;DR: 8T-0267 (CAS 866137-34-0) is a chemical compound with molecular formula C20H19F3N4O3 and molecular weight 420.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-oxo-4H-1,4-benzoxazin-6-yl)-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
Also Known As: 8T-0267, N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-4-[3-(trifluoromethyl)phenyl]tetrahydro-1(2H)-pyrazinecarboxamide, N-(3-oxo-4H-1,4-benzoxazin-6-yl)-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide, N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide, N-(3-oxo-2,4-dihydro-1,4-benzoxazin-6-yl)-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
| Molecular Formula | C20H19F3N4O3 |
|---|---|
| Molecular Weight | 420.14 g/mol |
| LogP | 3.3904 |
| Topological Polar Surface Area | 73.91 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 420.14093 |
| Heavy Atoms | 30 |
| Complexity | 972.00934 |
Chemical Identifiers
| CAS Number | 866137-34-0 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC(=C2)C(F)(F)F)C(=O)NC3=CC4=C(C=C3)OCC(=O)N4 |
Product Overview
8T-0267 (CAS 866137-34-0), with molecular formula C20H19F3N4O3 and molecular weight 420.14 g/mol. IUPAC: N-(3-oxo-4H-1,4-benzoxazin-6-yl)-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide.
Chemical Property Profile of 8T-0267
Property Insights of 8T-0267
The XLogP value of 3.3904 indicates that 8T-0267 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.91 Ų falls within the moderate polarity range, balancing permeability and solubility for 8T-0267. Following Lipinski's Rule of Five, 8T-0267 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8T-0267?
The CAS number of 8T-0267 is 866137-34-0.
What is the molecular formula of 8T-0267?
The molecular formula of 8T-0267 is C20H19F3N4O3.
What is the molecular weight of 8T-0267?
The molecular weight of 8T-0267 is 420.14 g/mol.
Where can I buy 8T-0267?
You can request a quote for 8T-0267 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8T-0267?
Yes, KEHONG BIO provides custom synthesis services for 8T-0267 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.