N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide
TL;DR: N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide (CAS 866137-32-8) is a chemical compound with molecular formula C19H21ClFN3O2 and molecular weight 377.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(3-chloro-4-methoxyphenyl)methyl]-4-(4-fluorophenyl)piperazine-1-carboxamide
Also Known As: N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide, N-[(3-chloro-4-methoxyphenyl)methyl]-4-(4-fluorophenyl)piperazine-1-carboxamide, N-[(3-chloro-4-methoxy-phenyl)methyl]-4-(4-fluorophenyl)piperazine-1-carboxamide, C19H21ClFN3O2
| Molecular Formula | C19H21ClFN3O2 |
|---|---|
| Molecular Weight | 377.13 g/mol |
| LogP | 3.5195 |
| Topological Polar Surface Area | 44.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 377.13065 |
| Heavy Atoms | 26 |
| Complexity | 761.8796 |
Chemical Identifiers
| CAS Number | 866137-32-8 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)CNC(=O)N2CCN(CC2)C3=CC=C(C=C3)F)Cl |
Product Overview
N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide (CAS 866137-32-8), with molecular formula C19H21ClFN3O2 and molecular weight 377.13 g/mol. IUPAC: N-[(3-chloro-4-methoxyphenyl)methyl]-4-(4-fluorophenyl)piperazine-1-carboxamide.
Chemical Property Profile of N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide
Property Insights of N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide
The XLogP value of 3.5195 indicates that N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.81 Ų, N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide?
The CAS number of N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide is 866137-32-8.
What is the molecular formula of N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide?
The molecular formula of N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide is C19H21ClFN3O2.
What is the molecular weight of N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide?
The molecular weight of N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide is 377.13 g/mol.
Where can I buy N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide?
You can request a quote for N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.