8P-345S
TL;DR: 8P-345S (CAS 866136-64-3) is a chemical compound with molecular formula C13H9F2N3OS2 and molecular weight 325.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2,4-difluorophenyl)sulfanyl-1-(6-methyl-[1,3]thiazolo[3,2-b][1,2,4]triazol-5-yl)ethanone
Also Known As: 8P-345S, 2-[(2,4-difluorophenyl)sulfanyl]-1-(6-methyl[1,3]thiazolo[3,2-b][1,2,4]triazol-5-yl)-1-ethanone, 2-(2,4-difluorophenyl)sulfanyl-1-(6-methyl-[1,3]thiazolo[3,2-b][1,2,4]triazol-5-yl)ethanone, 2-[(2,4-difluorophenyl)sulfanyl]-1-{6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl}ethan-1-one
| Molecular Formula | C13H9F2N3OS2 |
|---|---|
| Molecular Weight | 325.02 g/mol |
| LogP | 3.35242 |
| Topological Polar Surface Area | 47.26 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 325.0155 |
| Heavy Atoms | 21 |
| Complexity | 828.0458 |
Chemical Identifiers
| CAS Number | 866136-64-3 |
|---|---|
| SMILES | CC1=C(SC2=NC=NN12)C(=O)CSC3=C(C=C(C=C3)F)F |
Product Overview
8P-345S (CAS 866136-64-3), with molecular formula C13H9F2N3OS2 and molecular weight 325.02 g/mol. IUPAC: 2-(2,4-difluorophenyl)sulfanyl-1-(6-methyl-[1,3]thiazolo[3,2-b][1,2,4]triazol-5-yl)ethanone.
Chemical Property Profile of 8P-345S
Property Insights of 8P-345S
The XLogP value of 3.35242 indicates that 8P-345S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.26 Ų, 8P-345S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8P-345S has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8P-345S?
The CAS number of 8P-345S is 866136-64-3.
What is the molecular formula of 8P-345S?
The molecular formula of 8P-345S is C13H9F2N3OS2.
What is the molecular weight of 8P-345S?
The molecular weight of 8P-345S is 325.02 g/mol.
Where can I buy 8P-345S?
You can request a quote for 8P-345S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8P-345S?
Yes, KEHONG BIO provides custom synthesis services for 8P-345S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.