![3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone structure](/static/products/866/866132-73-2.png)
3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone
TL;DR: 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone (CAS 866132-73-2) is a chemical compound with molecular formula C13H12F3NO3 and molecular weight 287.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3E)-3-[1-[4-(trifluoromethoxy)anilino]ethylidene]oxolan-2-one
Also Known As: (3E)-3-(1-{[4-(trifluoromethoxy)phenyl]amino}ethylidene)oxolan-2-one, 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone, 7W-0227, (3E)-3-[1-[4-(trifluoromethoxy)anilino]ethylidene]oxolan-2-one, (3E)-3-[1-[4-(trifluoromethoxy)anilino]ethylidene]tetrahydrofuran-2-one
| Molecular Formula | C13H12F3NO3 |
|---|---|
| Molecular Weight | 287.08 g/mol |
| LogP | 3.218 |
| Topological Polar Surface Area | 47.56 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 287.07693 |
| Heavy Atoms | 20 |
| Complexity | 534.78754 |
Chemical Identifiers
| CAS Number | 866132-73-2 |
|---|---|
| SMILES | C/C(=C\1/CCOC1=O)/NC2=CC=C(C=C2)OC(F)(F)F |
Product Overview
3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone (CAS 866132-73-2), with molecular formula C13H12F3NO3 and molecular weight 287.08 g/mol. IUPAC: (3E)-3-[1-[4-(trifluoromethoxy)anilino]ethylidene]oxolan-2-one.
Chemical Property Profile of 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone
Property Insights of 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone
The XLogP value of 3.218 indicates that 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.56 Ų, 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone?
The CAS number of 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone is 866132-73-2.
What is the molecular formula of 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone?
The molecular formula of 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone is C13H12F3NO3.
What is the molecular weight of 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone?
The molecular weight of 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone is 287.08 g/mol.
Where can I buy 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone?
You can request a quote for 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone?
Yes, KEHONG BIO provides custom synthesis services for 3-{(E)-1-[4-(trifluoromethoxy)anilino]ethylidene}dihydro-2(3H)-furanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.