![3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one structure](/static/products/866/866050-75-1.png)
3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one
TL;DR: 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one (CAS 866050-75-1) is a chemical compound with molecular formula C12H7ClN2OS and molecular weight 262.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(2-chloro-1,3-thiazol-5-yl)methylidene]-1H-indol-2-one
Also Known As: 3-[(2-chlorothiazol-5-yl)methylene]indolin-2-one, 3-[(2-chloro-1,3-thiazol-5-yl)methylidene]-1H-indol-2-one, 3-[(E)-(2-chloro-1,3-thiazol-5-yl)methylidene]-1,3-dihydro-2H-indol-2-one
| Molecular Formula | C12H7ClN2OS |
|---|---|
| Molecular Weight | 262.00 g/mol |
| LogP | 3.2892 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 261.99677 |
| Heavy Atoms | 17 |
| Complexity | 632.9408 |
Chemical Identifiers
| CAS Number | 866050-75-1 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CC3=CN=C(S3)Cl)C(=O)N2 |
Product Overview
3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one (CAS 866050-75-1), with molecular formula C12H7ClN2OS and molecular weight 262.00 g/mol. IUPAC: 3-[(2-chloro-1,3-thiazol-5-yl)methylidene]-1H-indol-2-one.
Chemical Property Profile of 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one
Property Insights of 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one
The XLogP value of 3.2892 indicates that 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one?
The CAS number of 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one is 866050-75-1.
What is the molecular formula of 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one?
The molecular formula of 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one is C12H7ClN2OS.
What is the molecular weight of 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one?
The molecular weight of 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one is 262.00 g/mol.
Where can I buy 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one?
You can request a quote for 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 3-[(2-Chlorothiazol-5-yl)methylene]indolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.