![5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol structure](/static/products/866/86604-73-1.png)
5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol
TL;DR: 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol (CAS 86604-73-1) is a chemical compound with molecular formula C8H5F3N2S and molecular weight 218.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(trifluoromethyl)-1,3-dihydrobenzimidazole-2-thione
Also Known As: 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol, Maybridge1_006458, 6-(trifluoromethyl)-1H-1,3-benzodiazole-2-thiol, 5-(trifluoromethyl)-1H-1,3-benzodiazole-2-thiol, 5-(trifluoromethyl) 2 benzimidazolethiol
| Molecular Formula | C8H5F3N2S |
|---|---|
| Molecular Weight | 218.01 g/mol |
| LogP | 3.24429 |
| Topological Polar Surface Area | 31.58 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 218.01256 |
| Heavy Atoms | 14 |
| Complexity | 523.1013 |
Chemical Identifiers
| CAS Number | 86604-73-1 |
|---|---|
| SMILES | C1=CC2=C(C=C1C(F)(F)F)NC(=S)N2 |
Product Overview
5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol (CAS 86604-73-1), with molecular formula C8H5F3N2S and molecular weight 218.01 g/mol. IUPAC: 5-(trifluoromethyl)-1,3-dihydrobenzimidazole-2-thione.
Chemical Property Profile of 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol
Property Insights of 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol
The XLogP value of 3.24429 indicates that 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 31.58 Ų, 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol?
The CAS number of 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol is 86604-73-1.
What is the molecular formula of 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol?
The molecular formula of 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol is C8H5F3N2S.
What is the molecular weight of 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol?
The molecular weight of 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol is 218.01 g/mol.
Where can I buy 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol?
You can request a quote for 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol?
Yes, KEHONG BIO provides custom synthesis services for 5-(trifluoromethyl)-1H-benzo[d]imidazole-2-thiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.