5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine
TL;DR: 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine (CAS 866017-85-8) is a chemical compound with molecular formula C20H16N4O2S2 and molecular weight 408.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine
Also Known As: 4R-1042, 5-(benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine, 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-pyrimidinamine
| Molecular Formula | C20H16N4O2S2 |
|---|---|
| Molecular Weight | 408.07 g/mol |
| LogP | 3.99052 |
| Topological Polar Surface Area | 98.83 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 408.07147 |
| Heavy Atoms | 28 |
| Complexity | 1237.958 |
Chemical Identifiers
| CAS Number | 866017-85-8 |
|---|---|
| SMILES | CC1=C(SC(=N1)C2=CC=CC=C2)C3=NC(=NC=C3S(=O)(=O)C4=CC=CC=C4)N |
Product Overview
5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine (CAS 866017-85-8), with molecular formula C20H16N4O2S2 and molecular weight 408.07 g/mol. IUPAC: 5-(benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine.
Chemical Property Profile of 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine
Property Insights of 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine
The XLogP value of 3.99052 indicates that 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 98.83 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine. Following Lipinski's Rule of Five, 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine?
The CAS number of 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine is 866017-85-8.
What is the molecular formula of 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine?
The molecular formula of 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine is C20H16N4O2S2.
What is the molecular weight of 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine?
The molecular weight of 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine is 408.07 g/mol.
Where can I buy 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine?
You can request a quote for 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 5-(Benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)pyrimidin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.