4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine
TL;DR: 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine (CAS 866017-83-6) is a chemical compound with molecular formula C24H17N3O2S3 and molecular weight 475.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[5-(benzenesulfonyl)-2-thiophen-2-ylpyrimidin-4-yl]-4-methyl-2-phenyl-1,3-thiazole
Also Known As: 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine, 5-(benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-(thiophen-2-yl)pyrimidine, 5-[5-(benzenesulfonyl)-2-thiophen-2-ylpyrimidin-4-yl]-4-methyl-2-phenyl-1,3-thiazole
| Molecular Formula | C24H17N3O2S3 |
|---|---|
| Molecular Weight | 475.05 g/mol |
| LogP | 6.13682 |
| Topological Polar Surface Area | 72.81 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 475.04828 |
| Heavy Atoms | 32 |
| Complexity | 1478.5638 |
Chemical Identifiers
| CAS Number | 866017-83-6 |
|---|---|
| SMILES | CC1=C(SC(=N1)C2=CC=CC=C2)C3=NC(=NC=C3S(=O)(=O)C4=CC=CC=C4)C5=CC=CS5 |
Product Overview
4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine (CAS 866017-83-6), with molecular formula C24H17N3O2S3 and molecular weight 475.05 g/mol. IUPAC: 5-[5-(benzenesulfonyl)-2-thiophen-2-ylpyrimidin-4-yl]-4-methyl-2-phenyl-1,3-thiazole.
Chemical Property Profile of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine
Property Insights of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine
The XLogP value of 6.13682 indicates that 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.81 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine. Following Lipinski's Rule of Five, 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine?
The CAS number of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine is 866017-83-6.
What is the molecular formula of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine?
The molecular formula of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine is C24H17N3O2S3.
What is the molecular weight of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine?
The molecular weight of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine is 475.05 g/mol.
Where can I buy 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine?
You can request a quote for 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(2-thienyl)pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.