4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine structure

4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine

TL;DR: 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine (CAS 866017-82-5) is a chemical compound with molecular formula C25H18N4O2S2 and molecular weight 470.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-[5-(benzenesulfonyl)-2-pyridin-3-ylpyrimidin-4-yl]-4-methyl-2-phenyl-1,3-thiazole

Also Known As: 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine, 5-(benzenesulfonyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-2-(pyridin-3-yl)pyrimidine, 5-[5-(benzenesulfonyl)-2-pyridin-3-ylpyrimidin-4-yl]-4-methyl-2-phenyl-1,3-thiazole, 5-[5-besyl-2-(3-pyridyl)pyrimidin-4-yl]-4-methyl-2-phenyl-thiazole, 4-methyl-2-phenyl-5-[5-(phenylsulfonyl)-2-pyridin-3-yl-pyrimidin-4-yl]-1,3-thiazole

CAS: 866017-82-5
Molecular Formula C25H18N4O2S2
Molecular Weight 470.09 g/mol
LogP 5.47032
Topological Polar Surface Area 85.7 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 470.08713
Heavy Atoms 33
Complexity 1519.2609

Chemical Identifiers

CAS Number 866017-82-5
SMILES CC1=C(SC(=N1)C2=CC=CC=C2)C3=NC(=NC=C3S(=O)(=O)C4=CC=CC=C4)C5=CN=CC=C5

Product Overview

4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine (CAS 866017-82-5), with molecular formula C25H18N4O2S2 and molecular weight 470.09 g/mol. IUPAC: 5-[5-(benzenesulfonyl)-2-pyridin-3-ylpyrimidin-4-yl]-4-methyl-2-phenyl-1,3-thiazole.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine

XLogP
5.47032
TPSA (Topological Polar Surface Area)
85.7
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
33
Complexity
1519.2609
Exact Mass
470.08713
Monoisotopic Mass
470.08713
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine

The XLogP value of 5.47032 indicates that 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine. Following Lipinski's Rule of Five, 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine?

The CAS number of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine is 866017-82-5.

What is the molecular formula of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine?

The molecular formula of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine is C25H18N4O2S2.

What is the molecular weight of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine?

The molecular weight of 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine is 470.09 g/mol.

Where can I buy 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine?

You can request a quote for 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine?

Yes, KEHONG BIO provides custom synthesis services for 4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-5-(phenylsulfonyl)-2-(3-pyridinyl)pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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