Tideglusib
TL;DR: Tideglusib (CAS 865854-05-3) is a chemical compound with molecular formula C20H24F2N4O and molecular weight 374.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(3,4-difluoroanilino)-N-[2-methyl-5-(piperazin-1-ylmethyl)phenyl]acetamide
Also Known As: Tideglusib, antagonist GW791343, GW 791343 Trihydrochloride, 2-[(3,4-difluorophenyl)amino]-N-[2-methyl-5-(piperazin-1-ylmethyl)phenyl]acetamide, N~2~-(3,4-Difluorophenyl)-N-{2-Methyl-5-[(Piperazin-1-Yl)methyl]phenyl}glycinamide
| Molecular Formula | C20H24F2N4O |
|---|---|
| Molecular Weight | 374.19 g/mol |
| LogP | 2.72902 |
| Topological Polar Surface Area | 56.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 374.1918 |
| Heavy Atoms | 27 |
| Complexity | 806.5639 |
Chemical Identifiers
| CAS Number | 865854-05-3 |
|---|---|
| SMILES | CC1=C(C=C(C=C1)CN2CCNCC2)NC(=O)CNC3=CC(=C(C=C3)F)F |
Product Overview
Tideglusib (CAS 865854-05-3), with molecular formula C20H24F2N4O and molecular weight 374.19 g/mol. IUPAC: 2-(3,4-difluoroanilino)-N-[2-methyl-5-(piperazin-1-ylmethyl)phenyl]acetamide.
Chemical Property Profile of Tideglusib
Property Insights of Tideglusib
The XLogP value of 2.72902 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tideglusib. With a topological polar surface area (TPSA) of 56.4 Ų, Tideglusib exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tideglusib has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tideglusib?
The CAS number of Tideglusib is 865854-05-3.
What is the molecular formula of Tideglusib?
The molecular formula of Tideglusib is C20H24F2N4O.
What is the molecular weight of Tideglusib?
The molecular weight of Tideglusib is 374.19 g/mol.
Where can I buy Tideglusib?
You can request a quote for Tideglusib directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tideglusib?
Yes, KEHONG BIO provides custom synthesis services for Tideglusib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.