1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine structure

1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine

TL;DR: 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine (CAS 865660-36-2) is a chemical compound with molecular formula C19H19N5S and molecular weight 349.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine

Also Known As: 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine, 1-(4-phenylpiperazin-1-yl)-N-[4-(thiophen-2-yl)pyrimidin-2-yl]methanimine, N-[(E)-(4-phenylpiperazino)methylidene]-4-(2-thienyl)-2-pyrimidinamine, (1E)-1-(4-phenylpiperazin-1-yl)-N-[4-(thiophen-2-yl)pyrimidin-2-yl]methanimine

CAS: 865660-36-2
Molecular Formula C19H19N5S
Molecular Weight 349.14 g/mol
LogP 3.6871
Topological Polar Surface Area 44.62 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 4
Exact Mass 349.1361
Heavy Atoms 25
Complexity 824.0404

Chemical Identifiers

CAS Number 865660-36-2
SMILES C1CN(CCN1C=NC2=NC=CC(=N2)C3=CC=CS3)C4=CC=CC=C4

Product Overview

1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine (CAS 865660-36-2), with molecular formula C19H19N5S and molecular weight 349.14 g/mol. IUPAC: 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine

XLogP
3.6871
TPSA (Topological Polar Surface Area)
44.62
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
25
Complexity
824.0404
Exact Mass
349.1361
Monoisotopic Mass
349.1361
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine

The XLogP value of 3.6871 indicates that 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.62 Ų, 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine?

The CAS number of 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine is 865660-36-2.

What is the molecular formula of 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine?

The molecular formula of 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine is C19H19N5S.

What is the molecular weight of 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine?

The molecular weight of 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine is 349.14 g/mol.

Where can I buy 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine?

You can request a quote for 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine?

Yes, KEHONG BIO provides custom synthesis services for 1-(4-phenylpiperazin-1-yl)-N-(4-thiophen-2-ylpyrimidin-2-yl)methanimine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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