(E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide
TL;DR: (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide (CAS 865545-92-2) is a chemical compound with molecular formula C14H9ClN2OS and molecular weight 288.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)prop-2-enamide
Also Known As: (2E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)prop-2-enamide, (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide, F1385-0068, (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)prop-2-enamide, 3-(2-Chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide
| Molecular Formula | C14H9ClN2OS |
|---|---|
| Molecular Weight | 288.01 g/mol |
| LogP | 3.92508 |
| Topological Polar Surface Area | 52.89 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 288.01242 |
| Heavy Atoms | 19 |
| Complexity | 670.0806 |
Chemical Identifiers
| CAS Number | 865545-92-2 |
|---|---|
| SMILES | C1=CC=C(C(=C1)/C=C/C(=O)NC2=C(C=CS2)C#N)Cl |
Product Overview
(E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide (CAS 865545-92-2), with molecular formula C14H9ClN2OS and molecular weight 288.01 g/mol. IUPAC: (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)prop-2-enamide.
Chemical Property Profile of (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide
Property Insights of (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide
The XLogP value of 3.92508 indicates that (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.89 Ų, (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide?
The CAS number of (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide is 865545-92-2.
What is the molecular formula of (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide?
The molecular formula of (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide is C14H9ClN2OS.
What is the molecular weight of (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide?
The molecular weight of (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide is 288.01 g/mol.
Where can I buy (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide?
You can request a quote for (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(2-chlorophenyl)-N-(3-cyanothiophen-2-yl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.