N-(Phenoxyacetyl)deacetylcolchicine
TL;DR: N-(Phenoxyacetyl)deacetylcolchicine (CAS 86436-45-5) is a chemical compound with molecular formula C28H29NO7 and molecular weight 491.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-phenoxy-N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide
Also Known As: N-(Phenoxyacetyl)deacetylcolchicine, Colchicine, N-desacetyl-N-phenyloxyacetyl-, Acetamide, 2-phenoxy-N-(5,6,7,9-tetrahydro-9-oxo-1,2,3,10-tetramethoxybenzo(a)heptalen-7-yl)-, (S)-, 2-Phenoxy-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide, 2-phenoxy-N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide
| Molecular Formula | C28H29NO7 |
|---|---|
| Molecular Weight | 491.19 g/mol |
| LogP | 2.7 |
| Topological Polar Surface Area | 92.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 491.1944 |
| Heavy Atoms | 36 |
| Complexity | 888.0 |
Chemical Identifiers
| CAS Number | 86436-45-5 |
|---|---|
| SMILES | COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)COC4=CC=CC=C4 |
| InChIKey | GQILPBLGDOWLSP-UHFFFAOYSA-N |
Product Overview
N-(Phenoxyacetyl)deacetylcolchicine (CAS 86436-45-5), with molecular formula C28H29NO7 and molecular weight 491.19 g/mol. IUPAC: 2-phenoxy-N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide.
Chemical Property Profile of N-(Phenoxyacetyl)deacetylcolchicine
Property Insights of N-(Phenoxyacetyl)deacetylcolchicine
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(Phenoxyacetyl)deacetylcolchicine. The TPSA of 92.3 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(Phenoxyacetyl)deacetylcolchicine. Following Lipinski's Rule of Five, N-(Phenoxyacetyl)deacetylcolchicine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(Phenoxyacetyl)deacetylcolchicine?
The CAS number of N-(Phenoxyacetyl)deacetylcolchicine is 86436-45-5.
What is the molecular formula of N-(Phenoxyacetyl)deacetylcolchicine?
The molecular formula of N-(Phenoxyacetyl)deacetylcolchicine is C28H29NO7.
What is the molecular weight of N-(Phenoxyacetyl)deacetylcolchicine?
The molecular weight of N-(Phenoxyacetyl)deacetylcolchicine is 491.19 g/mol.
Where can I buy N-(Phenoxyacetyl)deacetylcolchicine?
You can request a quote for N-(Phenoxyacetyl)deacetylcolchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(Phenoxyacetyl)deacetylcolchicine?
Yes, KEHONG BIO provides custom synthesis services for N-(Phenoxyacetyl)deacetylcolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.