2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
TL;DR: 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one (CAS 862490-11-7) is a chemical compound with molecular formula C26H28N4O2 and molecular weight 428.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydro-6H-quinazolin-5-one
Also Known As: 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one, 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydro-6H-quinazolin-5-one, 2-(4-BENZYLPIPERAZIN-1-YL)-7-(4-METHOXYPHENYL)-5,6,7,8-TETRAHYDROQUINAZOLIN-5-ONE, 2-(4-benzylpiperazino)-7-(4-methoxyphenyl)-7,8-dihydro-6H-quinazolin-5-one, 7-(4-methoxyphenyl)-2-[4-(phenylmethyl)-1-piperazinyl]-7,8-dihydro-6H-quinazolin-5-one
| Molecular Formula | C26H28N4O2 |
|---|---|
| Molecular Weight | 428.22 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 58.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 428.22122 |
| Heavy Atoms | 32 |
| Complexity | 609.0 |
Chemical Identifiers
| CAS Number | 862490-11-7 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2CC3=NC(=NC=C3C(=O)C2)N4CCN(CC4)CC5=CC=CC=C5 |
| InChIKey | INKFNGXPLFWEDG-UHFFFAOYSA-N |
Product Overview
2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one (CAS 862490-11-7), with molecular formula C26H28N4O2 and molecular weight 428.22 g/mol. IUPAC: 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydro-6H-quinazolin-5-one.
Chemical Property Profile of 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
Property Insights of 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one
The XLogP value of 3.5 indicates that 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.6 Ų, 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one?
The CAS number of 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one is 862490-11-7.
What is the molecular formula of 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one?
The molecular formula of 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one is C26H28N4O2.
What is the molecular weight of 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one?
The molecular weight of 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one is 428.22 g/mol.
Where can I buy 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one?
You can request a quote for 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-benzylpiperazin-1-yl)-7-(4-methoxyphenyl)-7,8-dihydroquinazolin-5(6H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.