1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one
TL;DR: 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one (CAS 862486-67-7) is a chemical compound with molecular formula C21H22N4O3 and molecular weight 378.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2-one
Also Known As: 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one, F3226-3073, 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2-one, 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)-1,2-dihydroquinolin-2-one, 1-ethyl-3-nitro-4-(4-phenylpiperazinyl)hydroquinolin-2-one
| Molecular Formula | C21H22N4O3 |
|---|---|
| Molecular Weight | 378.17 g/mol |
| LogP | 3.2562 |
| Topological Polar Surface Area | 71.62 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 378.1692 |
| Heavy Atoms | 28 |
| Complexity | 1070.196 |
Chemical Identifiers
| CAS Number | 862486-67-7 |
|---|---|
| SMILES | CCN1C2=CC=CC=C2C(=C(C1=O)[N+](=O)[O-])N3CCN(CC3)C4=CC=CC=C4 |
Product Overview
1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one (CAS 862486-67-7), with molecular formula C21H22N4O3 and molecular weight 378.17 g/mol. IUPAC: 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2-one.
Chemical Property Profile of 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one
Property Insights of 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one
The XLogP value of 3.2562 indicates that 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.62 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one. Following Lipinski's Rule of Five, 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one?
The CAS number of 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one is 862486-67-7.
What is the molecular formula of 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one?
The molecular formula of 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one is C21H22N4O3.
What is the molecular weight of 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one?
The molecular weight of 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one is 378.17 g/mol.
Where can I buy 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one?
You can request a quote for 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 1-ethyl-3-nitro-4-(4-phenylpiperazin-1-yl)quinolin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.