![(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione structure](/static/products/862/862485-79-8.png)
(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione
TL;DR: (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione (CAS 862485-79-8) is a chemical compound with molecular formula C24H21FN2O4S and molecular weight 452.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)-hydroxymethylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione
Also Known As: (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione, (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)-hydroxymethylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione, 1-(4,5-dimethylthiazol-2-yl)-4-(4-ethoxybenzoyl)-5-(2-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one
| Molecular Formula | C24H21FN2O4S |
|---|---|
| Molecular Weight | 452.12 g/mol |
| LogP | 4.92404 |
| Topological Polar Surface Area | 79.73 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 452.1206 |
| Heavy Atoms | 32 |
| Complexity | 1213.5511 |
Chemical Identifiers
| CAS Number | 862485-79-8 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)/C(=C\2/C(N(C(=O)C2=O)C3=NC(=C(S3)C)C)C4=CC=CC=C4F)/O |
Product Overview
(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione (CAS 862485-79-8), with molecular formula C24H21FN2O4S and molecular weight 452.12 g/mol. IUPAC: (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)-hydroxymethylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione.
Chemical Property Profile of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione
Property Insights of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione
The XLogP value of 4.92404 indicates that (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.73 Ų falls within the moderate polarity range, balancing permeability and solubility for (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione. Following Lipinski's Rule of Five, (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione?
The CAS number of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione is 862485-79-8.
What is the molecular formula of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione?
The molecular formula of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione is C24H21FN2O4S.
What is the molecular weight of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione?
The molecular weight of (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione is 452.12 g/mol.
Where can I buy (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione?
You can request a quote for (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[(4-ethoxyphenyl)(hydroxy)methylidene]-5-(2-fluorophenyl)pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.