(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide structure

(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide

TL;DR: (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide (CAS 862129-39-3) is a chemical compound with molecular formula C21H16N8O3S and molecular weight 460.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(2-methoxynaphthalen-1-yl)methylideneamino]-5-thiophen-2-yltriazole-4-carboxamide

Also Known As: (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide, 1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-[(E)-(2-methoxynaphthalen-1-yl)methylidene]-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide, 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(2-methoxynaphthalen-1-yl)methylideneamino]-5-thiophen-2-yltriazole-4-carboxamide

CAS: 862129-39-3
Molecular Formula C21H16N8O3S
Molecular Weight 460.11 g/mol
LogP 2.8867
Topological Polar Surface Area 146.34 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 10
Rotatable Bonds 6
Exact Mass 460.1066
Heavy Atoms 33
Complexity 1472.2389

Chemical Identifiers

CAS Number 862129-39-3
SMILES COC1=C(C2=CC=CC=C2C=C1)/C=N/NC(=O)C3=C(N(N=N3)C4=NON=C4N)C5=CC=CS5

Product Overview

(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide (CAS 862129-39-3), with molecular formula C21H16N8O3S and molecular weight 460.11 g/mol. IUPAC: 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(2-methoxynaphthalen-1-yl)methylideneamino]-5-thiophen-2-yltriazole-4-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide

XLogP
2.8867
TPSA (Topological Polar Surface Area)
146.34
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
10
Rotatable Bonds
6
Heavy Atoms
33
Complexity
1472.2389
Exact Mass
460.1066
Monoisotopic Mass
460.1066
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide

The XLogP value of 2.8867 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide. The TPSA of 146.34 Ų indicates high polarity, suggesting (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide?

The CAS number of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide is 862129-39-3.

What is the molecular formula of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide?

The molecular formula of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide is C21H16N8O3S.

What is the molecular weight of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide?

The molecular weight of (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide is 460.11 g/mol.

Where can I buy (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide?

You can request a quote for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide?

Yes, KEHONG BIO provides custom synthesis services for (E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-((2-methoxynaphthalen-1-yl)methylene)-5-(thiophen-2-yl)-1H-1,2,3-triazole-4-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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