ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate structure

ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate

TL;DR: ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate (CAS 861645-22-9) is a chemical compound with molecular formula C26H29F3N4O4 and molecular weight 518.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 5-ethoxy-3-[[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]acetyl]amino]-1H-indole-2-carboxylate

Also Known As: ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate, ethyl 5-ethoxy-3-[({4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}acetyl)amino]-1H-indole-2-carboxylate, ethyl 5-ethoxy-3-[[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]acetyl]amino]-1H-indole-2-carboxylate

CAS: 861645-22-9
Molecular Formula C26H29F3N4O4
Molecular Weight 518.21 g/mol
LogP 4.5228
Topological Polar Surface Area 86.9 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 6
Rotatable Bonds 8
Exact Mass 518.2141
Heavy Atoms 37
Complexity 1266.4305

Chemical Identifiers

CAS Number 861645-22-9
SMILES CCOC1=CC2=C(C=C1)NC(=C2NC(=O)CN3CCN(CC3)C4=CC=CC(=C4)C(F)(F)F)C(=O)OCC

Product Overview

ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate (CAS 861645-22-9), with molecular formula C26H29F3N4O4 and molecular weight 518.21 g/mol. IUPAC: ethyl 5-ethoxy-3-[[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]acetyl]amino]-1H-indole-2-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate

XLogP
4.5228
TPSA (Topological Polar Surface Area)
86.9
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
6
Rotatable Bonds
8
Heavy Atoms
37
Complexity
1266.4305
Exact Mass
518.2141
Monoisotopic Mass
518.2141
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate

The XLogP value of 4.5228 indicates that ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.9 Ų falls within the moderate polarity range, balancing permeability and solubility for ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate. Following Lipinski's Rule of Five, ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate?

The CAS number of ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate is 861645-22-9.

What is the molecular formula of ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate?

The molecular formula of ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate is C26H29F3N4O4.

What is the molecular weight of ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate?

The molecular weight of ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate is 518.21 g/mol.

Where can I buy ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate?

You can request a quote for ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate?

Yes, KEHONG BIO provides custom synthesis services for ethyl 5-ethoxy-3-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)acetamido)-1H-indole-2-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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