![(Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one structure](/static/products/861/861643-79-0.png)
(Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one
TL;DR: (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one (CAS 861643-79-0) is a chemical compound with molecular formula C18H12N4O2S2 and molecular weight 380.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[4-hydroxy-5-(indol-3-ylidenemethyl)-2-sulfanylidene-1,3-thiazol-3-yl]pyridine-4-carboxamide
Also Known As: F3003-0193, (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one, N-[(5Z)-5-[(1H-indol-3-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]pyridine-4-carboxamide
| Molecular Formula | C18H12N4O2S2 |
|---|---|
| Molecular Weight | 380.04 g/mol |
| LogP | 4.02009 |
| Topological Polar Surface Area | 79.51 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 380.04016 |
| Heavy Atoms | 26 |
| Complexity | 1113.7198 |
Chemical Identifiers
| CAS Number | 861643-79-0 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CC3=C(N(C(=S)S3)NC(=O)C4=CC=NC=C4)O)C=N2 |
Product Overview
(Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one (CAS 861643-79-0), with molecular formula C18H12N4O2S2 and molecular weight 380.04 g/mol. IUPAC: N-[4-hydroxy-5-(indol-3-ylidenemethyl)-2-sulfanylidene-1,3-thiazol-3-yl]pyridine-4-carboxamide.
Chemical Property Profile of (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one
Property Insights of (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one
The XLogP value of 4.02009 indicates that (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.51 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one. Following Lipinski's Rule of Five, (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one?
The CAS number of (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one is 861643-79-0.
What is the molecular formula of (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one?
The molecular formula of (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one is C18H12N4O2S2.
What is the molecular weight of (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one?
The molecular weight of (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one is 380.04 g/mol.
Where can I buy (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one?
You can request a quote for (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-5-[(3-indolyl)methylene]-3-isonicotinoylamino-2-thioxo-1,3-thiazolidin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.