![1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine structure](/static/products/861/861212-85-3.png)
1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine
TL;DR: 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine (CAS 861212-85-3) is a chemical compound with molecular formula C11H11F6N3 and molecular weight 299.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3,5-bis(trifluoromethyl)-2-pyridinyl]piperazine
Also Known As: 1-[3,5-bis(trifluoromethyl)pyridin-2-yl]piperazine, 1-[3,5-bis(trifluoromethyl)-2-pyridinyl]piperazine, 1-[3,5-bis(trifluoromethyl)-2-pyridyl]piperazine, 3T-0220
| Molecular Formula | C11H11F6N3 |
|---|---|
| Molecular Weight | 299.09 g/mol |
| LogP | 2.5288 |
| Topological Polar Surface Area | 28.16 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 299.08572 |
| Heavy Atoms | 20 |
| Complexity | 476.0273 |
Chemical Identifiers
| CAS Number | 861212-85-3 |
|---|---|
| SMILES | C1CN(CCN1)C2=C(C=C(C=N2)C(F)(F)F)C(F)(F)F |
Product Overview
1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine (CAS 861212-85-3), with molecular formula C11H11F6N3 and molecular weight 299.09 g/mol. IUPAC: 1-[3,5-bis(trifluoromethyl)-2-pyridinyl]piperazine.
Chemical Property Profile of 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine
Property Insights of 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine
The XLogP value of 2.5288 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine. With a topological polar surface area (TPSA) of 28.16 Ų, 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine?
The CAS number of 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine is 861212-85-3.
What is the molecular formula of 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine?
The molecular formula of 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine is C11H11F6N3.
What is the molecular weight of 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine?
The molecular weight of 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine is 299.09 g/mol.
Where can I buy 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine?
You can request a quote for 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-[3,5-Bis(trifluoromethyl)pyridin-2-yl]piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.