2W-0819
TL;DR: 2W-0819 (CAS 861210-48-2) is a chemical compound with molecular formula C21H18N4OS and molecular weight 374.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3,3-dimethyl-1-[3-(3-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]azetidin-2-one
Also Known As: 2W-0819, 3,3-DIMETHYL-1-(3-[3-(2-THIENYL)PYRAZOLO[1,5-A]PYRIMIDIN-7-YL]PHENYL)-2-AZETANONE, 3,3-dimethyl-1-[3-(3-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]azetidin-2-one, 3,3-dimethyl-1-{3-[3-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl}azetidin-2-one, 3,3-dimethyl-1-{3-[3-(2-thienyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl}-2-azetanone
| Molecular Formula | C21H18N4OS |
|---|---|
| Molecular Weight | 374.12 g/mol |
| LogP | 4.4976 |
| Topological Polar Surface Area | 50.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 374.12012 |
| Heavy Atoms | 27 |
| Complexity | 1160.1246 |
Chemical Identifiers
| CAS Number | 861210-48-2 |
|---|---|
| SMILES | CC1(CN(C1=O)C2=CC=CC(=C2)C3=CC=NC4=C(C=NN34)C5=CC=CS5)C |
Product Overview
2W-0819 (CAS 861210-48-2), with molecular formula C21H18N4OS and molecular weight 374.12 g/mol. IUPAC: 3,3-dimethyl-1-[3-(3-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]azetidin-2-one.
Chemical Property Profile of 2W-0819
Property Insights of 2W-0819
The XLogP value of 4.4976 indicates that 2W-0819 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.5 Ų, 2W-0819 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2W-0819 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2W-0819?
The CAS number of 2W-0819 is 861210-48-2.
What is the molecular formula of 2W-0819?
The molecular formula of 2W-0819 is C21H18N4OS.
What is the molecular weight of 2W-0819?
The molecular weight of 2W-0819 is 374.12 g/mol.
Where can I buy 2W-0819?
You can request a quote for 2W-0819 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2W-0819?
Yes, KEHONG BIO provides custom synthesis services for 2W-0819 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.