![N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide structure](/static/products/860/860787-41-3.png)
N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide
TL;DR: N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide (CAS 860787-41-3) is a chemical compound with molecular formula C19H14ClN5OS and molecular weight 395.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[[1-[(2-chloro-1,3-thiazol-5-yl)methyl]indol-3-yl]methylideneamino]pyridine-4-carboxamide
Also Known As: N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide, 4-Pyridinecarboxylic acid, 2-[[1-[(2-chloro-5-thiazolyl)methyl]-1H-indol-3-yl]methylene]hydrazide, N'-({1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)pyridine-4-carbohydrazide, N-[(E)-[1-[(2-chloro-1,3-thiazol-5-yl)methyl]indol-3-yl]methylideneamino]pyridine-4-carboxamide, N-[[1-[(2-chloro-1,3-thiazol-5-yl)methyl]indol-3-yl]methylideneamino]pyridine-4-carboxamide
| Molecular Formula | C19H14ClN5OS |
|---|---|
| Molecular Weight | 395.06 g/mol |
| LogP | 3.9584 |
| Topological Polar Surface Area | 72.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 395.06076 |
| Heavy Atoms | 27 |
| Complexity | 1119.5549 |
Chemical Identifiers
| CAS Number | 860787-41-3 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2CC3=CN=C(S3)Cl)C=NNC(=O)C4=CC=NC=C4 |
Product Overview
N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide (CAS 860787-41-3), with molecular formula C19H14ClN5OS and molecular weight 395.06 g/mol. IUPAC: N-[[1-[(2-chloro-1,3-thiazol-5-yl)methyl]indol-3-yl]methylideneamino]pyridine-4-carboxamide.
Chemical Property Profile of N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide
Property Insights of N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide
The XLogP value of 3.9584 indicates that N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.17 Ų falls within the moderate polarity range, balancing permeability and solubility for N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide. Following Lipinski's Rule of Five, N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide?
The CAS number of N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide is 860787-41-3.
What is the molecular formula of N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide?
The molecular formula of N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide is C19H14ClN5OS.
What is the molecular weight of N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide?
The molecular weight of N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide is 395.06 g/mol.
Where can I buy N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide?
You can request a quote for N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide?
Yes, KEHONG BIO provides custom synthesis services for N'-((E)-{1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylidene)isonicotinohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.