12E-363S
TL;DR: 12E-363S (CAS 860784-61-8) is a chemical compound with molecular formula C23H17FN2O2S and molecular weight 404.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1'-benzyl-3-(4-fluorophenyl)spiro[1,3-thiazolidine-2,3'-indole]-2',4-dione
Also Known As: 12E-363S, 1-benzyl-3'-(4-fluorophenyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione, 1'-benzyl-3-(4-fluorophenyl)spiro[1,3-thiazolidine-2,3'-indole]-2',4-dione, spiro 3-[1-benzyl oxindyl]-2'-[3'-(4-flourophenyl)thiazolidin-4-one], 1-BENZYL-3'-(4-FLUOROPHENYL)SPIRO[INDOLE-3,2'-[1,3]THIAZOLIDINE]-2,4'-DIONE
| Molecular Formula | C23H17FN2O2S |
|---|---|
| Molecular Weight | 404.10 g/mol |
| LogP | 4.3053 |
| Topological Polar Surface Area | 40.62 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 404.0995 |
| Heavy Atoms | 29 |
| Complexity | 1103.3754 |
Chemical Identifiers
| CAS Number | 860784-61-8 |
|---|---|
| SMILES | C1C(=O)N(C2(S1)C3=CC=CC=C3N(C2=O)CC4=CC=CC=C4)C5=CC=C(C=C5)F |
Product Overview
12E-363S (CAS 860784-61-8), with molecular formula C23H17FN2O2S and molecular weight 404.10 g/mol. IUPAC: 1'-benzyl-3-(4-fluorophenyl)spiro[1,3-thiazolidine-2,3'-indole]-2',4-dione.
Chemical Property Profile of 12E-363S
Property Insights of 12E-363S
The XLogP value of 4.3053 indicates that 12E-363S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.62 Ų, 12E-363S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 12E-363S has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 12E-363S?
The CAS number of 12E-363S is 860784-61-8.
What is the molecular formula of 12E-363S?
The molecular formula of 12E-363S is C23H17FN2O2S.
What is the molecular weight of 12E-363S?
The molecular weight of 12E-363S is 404.10 g/mol.
Where can I buy 12E-363S?
You can request a quote for 12E-363S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 12E-363S?
Yes, KEHONG BIO provides custom synthesis services for 12E-363S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.