3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one
TL;DR: 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one (CAS 860784-41-4) is a chemical compound with molecular formula C17H17N3OS and molecular weight 311.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(2-piperidin-1-yl-1,3-thiazol-5-yl)methylidene]-1H-indol-2-one
Also Known As: 3-[(2-piperidin-1-yl-1,3-thiazol-5-yl)methylidene]-1H-indol-2-one, 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one, 3-[(Z)-(2-piperidino-1,3-thiazol-5-yl)methylidene]-1H-indol-2-one, 3-{[2-(piperidin-1-yl)-1,3-thiazol-5-yl]methylidene}-1H-indol-2-one
| Molecular Formula | C17H17N3OS |
|---|---|
| Molecular Weight | 311.11 g/mol |
| LogP | 3.6261 |
| Topological Polar Surface Area | 45.23 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 311.10922 |
| Heavy Atoms | 22 |
| Complexity | 743.86725 |
Chemical Identifiers
| CAS Number | 860784-41-4 |
|---|---|
| SMILES | C1CCN(CC1)C2=NC=C(S2)C=C3C4=CC=CC=C4NC3=O |
Product Overview
3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one (CAS 860784-41-4), with molecular formula C17H17N3OS and molecular weight 311.11 g/mol. IUPAC: 3-[(2-piperidin-1-yl-1,3-thiazol-5-yl)methylidene]-1H-indol-2-one.
Chemical Property Profile of 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one
Property Insights of 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one
The XLogP value of 3.6261 indicates that 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.23 Ų, 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one?
The CAS number of 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one is 860784-41-4.
What is the molecular formula of 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one?
The molecular formula of 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one is C17H17N3OS.
What is the molecular weight of 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one?
The molecular weight of 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one is 311.11 g/mol.
Where can I buy 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one?
You can request a quote for 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 3-((2-(Piperidin-1-yl)thiazol-5-yl)methylene)indolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.