1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine structure

1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine

TL;DR: 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine (CAS 860027-49-2) is a chemical compound with molecular formula C10H12F3N3 and molecular weight 231.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[5-(trifluoromethyl)-2-pyridinyl]piperazine

Also Known As: 1-[5-(trifluoromethyl)pyridin-2-yl]piperazine, 1-(5-(Trifluoromethyl)pyridin-2-yl)piperazine, 4-Bromotriphenylamine, 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine, 1-[5-(trifluoromethyl)pyrid-2-yl]piperazine

CAS: 860027-49-2
Molecular Formula C10H12F3N3
Molecular Weight 231.10 g/mol
LogP 1.5
Topological Polar Surface Area 28.2 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 1
Exact Mass 231.09833
Heavy Atoms 16
Complexity 226.0

Chemical Identifiers

CAS Number 860027-49-2
SMILES C1CN(CCN1)C2=NC=C(C=C2)C(F)(F)F
InChIKey BNMSJUIMZULLAS-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (2 patents) Heterocyclic Building Blocks (268 patents) Organic Building Blocks (5 patents) Organometallic Reagents (1 patents) Pharmaceutical Intermediates (166 patents)

Product Overview

1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine (CAS 860027-49-2), with molecular formula C10H12F3N3 and molecular weight 231.10 g/mol. IUPAC: 1-[5-(trifluoromethyl)-2-pyridinyl]piperazine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine

XLogP
1.5
TPSA (Topological Polar Surface Area)
28.2
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
1
Heavy Atoms
16
Complexity
226.0
Exact Mass
231.09833
Monoisotopic Mass
231.09833
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine

The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine. With a topological polar surface area (TPSA) of 28.2 Ų, 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine?

The CAS number of 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine is 860027-49-2.

What is the molecular formula of 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine?

The molecular formula of 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine is C10H12F3N3.

What is the molecular weight of 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine?

The molecular weight of 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine is 231.10 g/mol.

Where can I buy 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine?

You can request a quote for 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine?

Yes, KEHONG BIO provides custom synthesis services for 1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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