(E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one
TL;DR: (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one (CAS 859666-51-6) is a chemical compound with molecular formula C17H14O4 and molecular weight 282.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2E)-6-ethoxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one
Also Known As: (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one, (2E)-6-ethoxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one
| Molecular Formula | C17H14O4 |
|---|---|
| Molecular Weight | 282.09 g/mol |
| LogP | 3.4071 |
| Topological Polar Surface Area | 55.76 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 282.0892 |
| Heavy Atoms | 21 |
| Complexity | 714.07 |
Chemical Identifiers
| CAS Number | 859666-51-6 |
|---|---|
| SMILES | CCOC1=CC2=C(C=C1)C(=O)/C(=C\C3=CC=C(C=C3)O)/O2 |
Product Overview
(E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one (CAS 859666-51-6), with molecular formula C17H14O4 and molecular weight 282.09 g/mol. IUPAC: (2E)-6-ethoxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one.
Chemical Property Profile of (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one
Property Insights of (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one
The XLogP value of 3.4071 indicates that (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.76 Ų, (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one?
The CAS number of (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one is 859666-51-6.
What is the molecular formula of (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one?
The molecular formula of (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one is C17H14O4.
What is the molecular weight of (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one?
The molecular weight of (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one is 282.09 g/mol.
Where can I buy (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one?
You can request a quote for (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-6-ethoxy-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.