Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide
TL;DR: Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide (CAS 85901-57-1) is a chemical compound with molecular formula C26H31N5O6 and molecular weight 509.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-[[(2S)-4-methyl-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Pyr-Phe-Leu-Pna, Pglu-phe-leu-pna, pGlu-Phe-Leu p-nitroanilide, Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide, J2.281.167C
| Molecular Formula | C26H31N5O6 |
|---|---|
| Molecular Weight | 509.23 g/mol |
| LogP | 2.8 |
| Topological Polar Surface Area | 162.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 10 |
| Exact Mass | 509.22745 |
| Heavy Atoms | 37 |
| Complexity | 830.0 |
Chemical Identifiers
| CAS Number | 85901-57-1 |
|---|---|
| SMILES | CC(C)C[C@@H](C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H]3CCC(=O)N3 |
| InChIKey | NLVMZXVGZDVXDA-FKBYEOEOSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide (CAS 85901-57-1), with molecular formula C26H31N5O6 and molecular weight 509.23 g/mol. IUPAC: (2S)-N-[(2S)-1-[[(2S)-4-methyl-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide
Property Insights of Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide. The TPSA of 162.0 Ų indicates high polarity, suggesting Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide?
The CAS number of Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide is 85901-57-1.
What is the molecular formula of Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide?
The molecular formula of Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide is C26H31N5O6.
What is the molecular weight of Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide?
The molecular weight of Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide is 509.23 g/mol.
Where can I buy Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide?
You can request a quote for Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide?
Yes, KEHONG BIO provides custom synthesis services for Pyroglutamyl-phenylalanyl-leucine-4-nitroanilide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.