2',5-Difluoro-1-arabinosyluridine monophosphate
TL;DR: 2',5-Difluoro-1-arabinosyluridine monophosphate (CAS 85894-46-8) is a chemical compound with molecular formula C9H11F2N2O8P and molecular weight 344.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2R,3R,4S,5R)-4-fluoro-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
Also Known As: FF-Ara-ump, 2',5-Difluoro-1-arabinosyluridine monophosphate, 2',5-Difluoro-2'-deoxy-1-arabinosyluridylate, 1-(2-Deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione, [(2R,3R,4S,5R)-4-fluoro-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
| Molecular Formula | C9H11F2N2O8P |
|---|---|
| Molecular Weight | 344.02 g/mol |
| LogP | -2.8 |
| Topological Polar Surface Area | 146.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 4 |
| Exact Mass | 344.0221 |
| Heavy Atoms | 22 |
| Complexity | 566.0 |
Chemical Identifiers
| CAS Number | 85894-46-8 |
|---|---|
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)F)F |
| InChIKey | FEEBOLVDMGNROC-BYPJNBLXSA-N |
Product Overview
2',5-Difluoro-1-arabinosyluridine monophosphate (CAS 85894-46-8), with molecular formula C9H11F2N2O8P and molecular weight 344.02 g/mol. IUPAC: [(2R,3R,4S,5R)-4-fluoro-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate.
Chemical Property Profile of 2',5-Difluoro-1-arabinosyluridine monophosphate
Property Insights of 2',5-Difluoro-1-arabinosyluridine monophosphate
The XLogP value of -2.8 indicates that 2',5-Difluoro-1-arabinosyluridine monophosphate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 146.0 Ų indicates high polarity, suggesting 2',5-Difluoro-1-arabinosyluridine monophosphate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2',5-Difluoro-1-arabinosyluridine monophosphate has 4 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2',5-Difluoro-1-arabinosyluridine monophosphate?
The CAS number of 2',5-Difluoro-1-arabinosyluridine monophosphate is 85894-46-8.
What is the molecular formula of 2',5-Difluoro-1-arabinosyluridine monophosphate?
The molecular formula of 2',5-Difluoro-1-arabinosyluridine monophosphate is C9H11F2N2O8P.
What is the molecular weight of 2',5-Difluoro-1-arabinosyluridine monophosphate?
The molecular weight of 2',5-Difluoro-1-arabinosyluridine monophosphate is 344.02 g/mol.
Where can I buy 2',5-Difluoro-1-arabinosyluridine monophosphate?
You can request a quote for 2',5-Difluoro-1-arabinosyluridine monophosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2',5-Difluoro-1-arabinosyluridine monophosphate?
Yes, KEHONG BIO provides custom synthesis services for 2',5-Difluoro-1-arabinosyluridine monophosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.